This follow-up to the surprisingly successful WHAT THE BLEEP DO WE KNOW? takes a further look at quantum physics and how it affects our lives. Amanda (Marlee Matlin) doesn't know which way to turn, with both her personal and professional lives in turmoil. So a group of experts in different fields help Amanda to understand how her actions are connected to the human race as a whole, providing some thought-provoking concepts and in-depth analysis.